« Previous
Next »
Transfusion Medicine Reviews
Volume 20, Issue 3
, Pages 190-206
, July 2006
An Overview of Prion Biology and the Role of Blood Filtration in Reducing the Risk of Transfusion-Transmitted Variant Creutzfeldt-Jakob Disease
References
- Updated projections of future vCJD deaths in the UK. BMC Infect Dis. 2003;3:4
- Predicted vCJD mortality in Great Britain. Nature. 2000;406:583–584
- Estimation of the number of people incubating variant CJD. [letter] Lancet. 1998;352:1353–1354
- Human prion diseases: Epidemiology and integrated risk assessment. Lancet Neurol. 2003;2:757–763
- Prion biology in transfusion medicine: Implications for lab testing. MLO Med Lab Obs. 2005;10–22
- A new variant Creutzfeldt-Jakob disease in the UK. Lancet. 1996;347:921–925
- Further precautionary measures on blood products announced. Department of Health press release on CJD/BSE (United Kingdom 98/076). Feb 26,1998
- Is Creutzfeldt-Jakob disease transmitted in blood?. Emerg Infect Dis. 1997;3:157–163
- . Creutzfeldt-Jakob disease (CJD) investigational lookback study. Transfusion. 1997;37:2S;(suppl)
- . Creutzfeldt-Jakob disease in Canada. Can Commun Dis Rep. 1996;22:57–61
- . Prions and blood products. Ann Med. 2000;32:501–513
- Tissue distribution of bovine spongiform encephalopathy agent in primates after intravenous or oral infection. Lancet. 2004;363:422–428
- Transmission of SE by blood transfusion in sheep. Lancet. 2000;356:999–1000
- Transmission of prion disease by blood transfusion. J Gen Virol. 2002;83:2897–2905
- Diagnosis of new variant Creutzfeldt-Jakob disease by tonsil biopsy. Lancet. 1997;349:99–100
- Western Mail. August 22, 2005
- . Prions and the immune system: A journey through gut, spleen, and nerves. Adv Immunol. 2003;81:123–171
- Prevention of scrapie pathogenesis by transgenic expression of anti–prion protein antibodies. Science. 2001;294:178–182
- Soluble dimeric prion protein binds PrP(Sc) in vivo and antagonizes prion disease. Cell. 2003;113:49–60
- Interventional strategies against prion diseases. Nat Rev Neurosci. 2001;2:745–749
- Impaired prion replication in spleens of mice lacking functional follicular dendritic cells. Science. 2000;288:1257–1259
- UK Department of Health http://www.dh.gov.uk
- . Detection of prions in blood. Nat Med. 2005;11:982–985
- Possible transmission of new variant Creutzfeldt-Jakob disease by blood transfusion. Lancet. 2004;363:417–421
- Preclinical vCJD after blood transfusion in a PRNP codon 129 heterozygous patient. Lancet. 2004;364:527–529
- Prusiner SB. Prions-Nobel lecture, December 8, 1997. Accessed on September 14, 2005 at http://nobelprize.org/medicine/laureates/1997/prusiner-lecture.pdf
- . Prion research: The next frontiers. Nature. 1997;389:795–798
- . Novel proteinaceous infectious particles cause scrapie. Science. 1982;216:136–144
- Scrapie and cellular PrP isoforms are encoded by the same chromosomal gene. Cell. 1986;46:417–428
- Identification of scrapie prion protein–specific mRNA in scrapie-infected and uninfected brain. Nature. 1985;315:331–333
- A cellular gene encodes scrapie PrP 27-30 protein. Cell. 1985;40:735–746
- . Prion proteins: One surprise after another. Harvey Lect. 2002-2003;98:173–205
- Glycan-controlled epitopes of prion protein include a major determinant of susceptibility to sheep scrapie. J Virol. 2004;78:9270–9276
- Nearly ubiquitous tissue distribution of the scrapie agent precursor protein. Neurology. 1992;42:149–156
- . Cellular biology of prion diseases. Clin Microbiol Rev. 1999;12:429–444
- . Creutzfeldt-Jakob disease and scrapie prions. Alzheimer Dis Assoc Disord. 1989;3:52–78
- Scrapie prion protein contains a phosphatidylinositol glycolipid. Cell. 1987;51:229–240
- Novel antibody-lectin enzyme-linked immunosorbent assay that distinguishes prion proteins in sporadic and variant cases of Creutzfeldt-Jakob disease. J Clin Microbiol. 2005;43:1118–1126
- Discrimination between scrapie and bovine spongiform encephalopathy in sheep by molecular size, immunoreactivity, and glycoprofile of prion protein. J Clin Microbiol. 2004;42:972–980
- . The interplay of glycosylation and disulfide formation influences fibrillization in a prion protein fragment. Proc Natl Acad Sci U S A. 2003;100:7593–7598
- . Differences in proteinase K resistance and neuronal deposition of abnormal prion proteins characterize bovine spongiform encephalopathy (BSE) and scrapie strains. Mol Med. 1999;5:406–418
- . Scrapie infectivity and proteinase K–resistant prion protein in sheep placenta, brain, spleen, and lymph node: Implications for transmission and antemortem diagnosis. J Infect Dis. 1998;178:949–953
- Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein. Nature. 1992;356:577–582
- Prion protein is necessary for normal synaptic function. Nature. 1994;370:295–297
- Altered circadian activity rhythms and sleep in mice devoid of prion protein. Nature. 1996;380:639–642
- Mice devoid of PrP are resistant to scrapie. Cell. 1993;73:1339–1347
- Signal transduction through prion protein. Science. 2000;289:1925–1928
- Prion protein–deficient cells show altered response to oxidative stress due to decreased SOD-1 activity. Exp Neurol. 1997;146:104–112
- Normal prion protein has an activity like that of superoxide dismutase. J Biochem. 1999;344:1–5(Pt. 1)
- Impairment of superoxide dismutase activation by N-terminally truncated prion protein (PrP) in PrP-deficient neuronal cell line. Biochem Biophys Res Commun. 2003;308:660–667
- . Superoxide dismutase activity of cellular prion protein in vivo. Biol Chem. 2003;384:1279–1285
- Brain copper content and cuproenzyme activity do not vary with prion protein expression level. J Biol Chem. 2000;275:7455–7458
- The cellular prion protein (PrP) selectively binds to Bcl-2 in the yeast two-hybrid system: Identification of candidate proteins binding to prion protein. Brain Res Mol Brain Res. 1995;30:165–168
- . Glycolipid-anchored proteins in neuroblastoma cells form detergent-resistant complexes without caveolin. J Cell Biol. 1995;129:619–627
- The cellular isoform of the prion protein, PrPc, is associated with caveolae in mouse neuroblastoma (N2a) cells. Biochem Biophys Res Commun. 1995;210:753–759
- The human 37-kDa laminin receptor precursor interacts with the prion protein in eukaryotic cells. Nat Med. 1997;3:1383–1388
- Binding of disease-associated prion protein to plasminogen. Nature. 2000;408:479–483
- Binding of neural cell adhesion molecules (N-CAMs) to the cellular prion protein. J Mol Biol. 2001;314:1209–1225
- Cellular prion protein promotes Brucella infection into macrophages. J Exp Med. 2003;198:5–17
- . Dangerous liaisons between a microbe and the prion protein. J Exp Med. 2003;198:1–4
- . Why don't humans get scrapie from eating sheep? A possible explanation based on secondary structure predictions. Med Hypotheses. 2005;64:919–924
- Chronic wasting disease of elk: Transmissibility to humans examined by transgenic mouse models. J Neurosci. 2005;25:7944–7949
- Experimental transmission of chronic wasting disease agent from mule deer to cattle by the intracerebral route. J Vet Diagn Invest. 2005;17:276–281
- . Neuropathology and molecular biology of variant Creutzfeldt-Jakob disease. Curr Top Microbiol Immunol. 2004;284:133–159
- . The codon for the methionine at position 129 (M129) in the human prion protein provides an alternative initiation site for translation and renders individuals homozygous for M129 more susceptible to prion disease. Med Hypotheses. 2005;65:865–867
- Prion protein glycosylation. J Neurochem. 2005;93:793–801
- . Glycosylation of prion strains in transmissible spongiform encephalopathies. Aust J Vet. 2004;82:292–299
- Safe method for isolation of prion protein and diagnosis of Creutzfeldt-Jakob disease. J Virol Methods. 2005;130:133–139
- Analysis of mammalian scrapie protein by novel monoclonal antibodies recognizing distinct prion protein glycoforms: An immunoblot and immunohistochemical study at the light and electron microscopic levels. Brain Res Bull. 2005;65:155–162
- PrP glycoforms are associated in a strain-specific ratio in native PrPSc. J Gen Virol. 2005;86:2635–2644
- Anchorless prion protein results in infectious amyloid disease without clinical scrapie. Science. 2005;308:1435–1439
- Bovine prion protein gene (PRNP) promoter polymorphisms modulate PRNP expression and may be responsible for differences in BSE susceptibility. J Biol Chem. 2005;280:37408–37414
- . Birth of a prion: Spontaneous generation revisited. Cell. 2005;122:165–168
- . The AGAAAAGA palindrome in PrP is required to generate a productive PrPSc-PrPC complex that leads to prion propagation. J Biol Chem. 2005;280:27236–27243
- The most infectious prion protein particles. Nature. 2005;437:257–261
- . Uber eine eigenartige herdformige erkrankkung des zentralnervensystems. Z Ges Neurol Psychiatry. 1920;57:1–18
- . Uber eigenartige erkrankungen des zentralnervensystems mit bemerkenswerten anatomischen befunde (spastische pseudosklerose-encephomyelopathie mit disseminierten degenerationsherden). Z Ges Neurol Psychiatry. 1921;64:147–228
- Does the agent of scrapie replicate without nucleic acid?. Nature. 1967;214:764–766
- . Self-replication and scrapie. Nature. 1967;215:1043–1044
- . Experimental transmission of a kuru-like syndrome to chimpanzees. Nature. 1966;209:794–796
- A new variant of Creutzfeldt-Jakob Disease in the UK. Lancet. 1996;347:921–925
- Chronic wasting disease and potential transmission to humans. Emerg Infect Dis. 2004;10:977–984
- . Neuropathology and molecular biology of variant Creutzfeldt-Jakob Disease. Curr Top Microbiol Immunol. 2004;284:133–159
- Sporadic and familial CJD: Classification and characterization. Br Med Bull. 2003;66:213–239
- . “Life, Jim, but not as we know it”? Transmissible dementias and the prion protein. Br J Psychiatry. 1991;158:457–470
- . Diagnosis of dementia: Clinicopathologic correlations. Neurology. 1989;39:76–79
- . Central nervous system amyloidoses: A comparison of Alzheimer's disease and Creutzfeldt-Jakob disease. Neurology. 1989;39:1103–1105
- . Some speculations about prions, amyloid, and Alzheimer's disease. N Engl J Med. 1984;310:661–663
- Mortality from Alzheimer Disease—United States, 1979-1987 MMWR November 02, 1990; 39:785-786,788 http://www.cdc.gov/mmwr/preview/mmwrhtml/00001820.htm
- Clinical diagnosis of Alzheimer's disease: Report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology. 1984;34:939–944
- Prion disease-spongiform encephalopathies unveiled. Lancet. 1990;336:21–22
- . Suggested links between different types of dementias: Creutzfeldt-Jakob disease, Alzheimer disease, and retroviral CNS infections. Alzheimer Dis Assoc Disord. 1989;3:100–109
- . The impact of variant CJD on transfusion practices in the UK. Transfus Apheresis Sci. 2003;28:107–116
- The vCJD Working party of the Standing Advisory Committee on Transfusion Transmitted Infections. Creutzfeld-Jakob disease. Joint UKBTS/NIBSC Position statements, April, 2004: http://www.transfusionguidelines.org.uk/docs/pdfs/position_statement_01_2004_04.pdf
- . Prion disease and blood. Transfus Med. 1996;6:213–215
- Canadian Blood Services press release, August 15, 2005
- United Kingdom Spongiform Encephalopathy Advisory Committee (SEAC) Annual Report 1997-1998: p10. Department of Environment, Food and Rural Affairs:3/04 Page Street, London SW1P 4PO, England, UK
- . New variant Creutzfeldt-Jakob disease (nvCJD): The risk of transmission by blood transfusion and the potential benefit of leukocyte-reduction of blood components. Transfus Med Rev. 1999;13:75–83
- Effectiveness of leucoreduction for removal of infectivity of transmissible spongiform encephalopathies from blood. Lancet. 2004;364:529–531
- Removal of prion (PrP) from red cell concentrates (RCC) with prototype of a prion removal filter (PrRF). Transfusion. 2003;43:7A–8A(Abstr, Suppl)
- FDA final guidance—Revised preventive measures to reduce the possible risk of transmission of Creutzfeldt-Jakob Disease (CJD) and Variant Creutzfeldt-Jakob Disease (vCJD) by blood and blood products. US Department of Health and Human Services, Food and Drug Administration, Center for Biologics Evaluation and Research (CBER). January 2002
- The distribution of infectivity in blood components and plasma derivatives in experimental models of transmissible spongiform encephalopathy. Transfusion. 1998;38:810–816
- . Blood infectivity and the prospects for a diagnostic screening test in Creutzfeldt-Jakob disease. J Lab Clin Med. 2001;137:5–13
- Removal of exogenous (spiked) and endogenous prion infectivity from red cell concentrates using a new prototype of leukocyte reduction filter. Transfusion. 2005;45:1839–1844
- . Characterization of prion removal devices for blood products. Transfus Med Hematother. 2005;32:245–251
- Sowemimo-Coker SO, Pesci S, Andrade F, Removal of infectious prions from red cell concentrates with leukotrap affinity prion reduction filter. Vox Sang. [Epub ahead of print: http://www.blackwell-synergy.com/toc/vox/0/0]
- A direct relationship between the portioning of the pathogenic prion protein and transmissible spongiform encephalopathy infectivity during the purification of plasma proteins. Transfusion. 2001;41:449–455
- Human prion protein cDNA: Molecular cloning, chromosomal mapping, and biological implications. Science. 1986;233:364–367
- Scrapie and Creutzfeldt-Jakob disease prion proteins share physical properties and antigenic determinants. Proc Natl Acad Sci U S A. 1985;82:997–1001
- . A simple method for estimating fifty percent endpoint. Am J Hyg. 1938;27:493–497
- . Guide to the preparation, use and quality assurance of blood components. 11th ed.. Strasbourg: Council of Europe Publishing; 2004;
- Food and Drug Administration Department of Health and Human Services Recommendations and licensure requirements for leukocyte reduced blood products. Memorandum to all registered blood establishments, May 29, 1996.
- . Guidelines for the Blood Transfusion Services in the United Kingdom. 6th ed. Norwich: The Stationary Office; 2002;
- Effects of 3-5 log10 pre-storage leukocyte depletion on red cell storage and metabolism. Br J Haematol. 1994;87:363–368
- Storage of whole blood for up to 24 hours at ambient temperature prior to component preparation. Vox Sang. 1989;56:145–150
- . Liquid-stored red blood cells for transfusion. Vox Sang. 1999;76:67–77
- Interlaboratory comparison of red cell ATP, 2,3-diphosphoglycerate and hemolysis measurements. Vox Sang. 2005;89:44–48
- In: Brecher ME, Leger RL, Linden JV editor. Collection, preparation, storage and distribution of components from whole blood donation. Chapter 8. AABB Technical Manual. 15th ed. Bethesda: AAAB; 2005;p. 175–202
- . Storage parameters affecting red cell survival and functions after transfusion. Transfus Med Rev. 1999;13:275–276
- . In vivo regeneration of red cell 2,3-diphosphoglycerate following transfusion of DPG-depleted AS-1, AS-3 and CPDA-1 red cells. Br J Haematol. 1989;71:181–186
- . Preparation and preservation of red cells. Vox Sang. 1998;74:177–187(suppl 2)
- . Studies in red blood cell preservation. 1. Effect of other formed elements. Vox Sang. 1990;58:85–89
- . Should we demand fresh red blood cells for perioperative and critically ill patients?. Br J Anaesth. 2002;89:537–540
- Improved red blood cell preservation correlates with decreased loss of bands 3, 4.1, acetylcholinesterase and lipids in microvesicles. Blood. 1996;87:1612–1616
- The effects of leukocyte depletion on the generation and removal of microvesicles and prion related protein in blood components. Transfus Apheresis Sci. 2001;25:177–178
- In-vitro evaluation of PALL leukotrap affinity prion reduction filter as a secondary device following primary leucoreduction. Vox Sang. 2005;89:220–228
- A band 3-based macrocomplex of integral and peripheral proteins in the RBC membrane. Blood. 2003;101:4180–4188
- The application of a new quantitative assay for the monitoring of integrin-associated protein CD47 on red blood cells during storage and comparison with the expression of CD47 and phospatidylserine with flow cytometry. Transfusion. 2005;45:1496–1503
- Evaluation of in vivo red blood cell recovery after processing with a new filter designed to remove prions. Vox Sang. 2005;89:20;(abstr, suppl 2)
- The application of the precautionary principle to the blood system: The Canadian blood system's vCJD donor deferral policy. Transfus Med Rev. 2003;17:89–94
PII: S0887-7963(06)00012-5
doi: 10.1016/j.tmrv.2006.03.007
© 2006 Elsevier Inc. All rights reserved.
« Previous
Next »
Transfusion Medicine Reviews
Volume 20, Issue 3
, Pages 190-206
, July 2006
