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Transfusion Medicine Reviews
Volume 22, Issue 3
, Pages 177-187
, July 2008
Evidence for the Use of Recombinant Factor VIIa in the Prevention and Treatment of Bleeding in Patients Without Hemophilia
References
- . Use of human factor VIIa in the treatment of two hemophilia A patients with high-titer inhibitors. J Clin Invest. 1983;71:1836–1841
- Successful use of recombinant factor VIIa in patient with severe haemophilia A during synovectomy. Lancet. 1988;2:1193
- . A cell-based model of hemostasis. Thromb Haemost. 2001;85:958–965
- . The use of recombinant factor VIIa in the treatment of bleeding disorders. Blood. 2004;104:3858–3864
- . Recombinant factor VIIa: Clinical applications for an intravenous hemostatic agent with broad-spectrum potential. Expert Rev Cardiovasc Ther. 2004;2:661–674
- Intravenous rFVIIa administered for hemorrhage control in hypothermic coagulopathic swine with grade V liver injuries. J Trauma. 2001;50:721–729
- Treatment of traumatic bleeding with recombinant factor VIIa. Lancet. 1999;354:1879
- . Clinical experiences and current evidence for therapeutic recombinant factor VIIa treatment in nontrauma settings. Crit Care. 2005;9(Suppl 5):S29–S36
- . Challenges in the therapeutic use of a “so-called” universal hemostatic agent: Recombinant factor VIIa. Hematol Am Soc Hematol Educ Program. 2006;426–431
- . Use of recombinant activated factor VII in the management of medical and surgical bleeding: A critical review. Transfus Alternatives Transfus Med. 2006;8(Suppl 1):66–80
- . Recombinant-activated coagulation factor VIIa (NovoSeven): Current development. Vox Sang. 2007;92:281–288
- Recombinant factor VIIa for the prevention and treatment of bleeding in patients without haemophilia. Cochrane Database Syst Rev. 2007;2:CD005011
- . The use or rFVIIa in non-haemophilia bleeding contitions in paediatrics: A systematic review. Thromb Haemost. 2004;92:738–746
- . Efficacy and safety or recombinant factor VIIa for treatment of severe bleeding: A systematic review. Crit Care Med. 2005;33:883–890
- Empirical evidence of bias. Dimensions of methodological quality associated with estimates of treatment effects in controlled trials. JAMA. 1995;273:408–412
- . Systematic reviews in health care: Assessing the quality of controlled clinical trials. BMJ. 2001;323:42–46
- Recombinant factor VIIa as adjunctive therapy for bleeding control in severely injured trauma patients: Two parallel randomized, placebo-controlled, double-blind clinical trials. J Trauma. 2005;59:8–18
- Safety and efficacy of recombinant factor VIIa in patients with liver disease undergoing laparoscopic liver biopsy. Gastroenterology. 2002;123:118–126
- Effect of recombinant activated factor VII on perioperative blood loss in patients undergoing retropubic prostatectomy: A double-blind placebo-controlled randomised trial. Lancet. 2003;361:201–205
- Recombinant coagulation factor VIIa in major liver resection: A randomized, placebo-controlled, double-blind clinical trial. Anesthesiology. 2005;102:269–275
- Safety and hemostatic effect of recombinant activated factor VII in cirrhotic patients undergoing partial hepatectomy: A multicenter, randomized, double-blind, placebo-controlled trial. Am J Surg. 2006;191:245–249
- Efficacy and safety of repeated perioperative doses of recombinant factor VIIa in liver transplantation. Liver Transpl. 2005;11:973–979
- Safety and efficacy of a single bolus administration of recombinant factor VIIa in liver transplantation due to chronic liver disease. Liver Transpl. 2005;11:895–900
- . Predicting response to recombinant factor VIIa in non-haemophiliac patients with severe haemorrhage. Br J Anaesth. 2006;97:476–481
- Use of activated recombinant coagulation factor VII in patients undergoing reconstruction surgery or traumatic fracture of pelvis or pelvis and acetabulum: A double-blind, randomized, placebo-controlled trial. Br J Anaesth. 2005;94:586–591
- Activated recombinant factor VII after cardiopulmonary bypass reduces allogeneic transfusion in complex non-coronary cardiac surgery: Randomized double-blind placebo-controlled pilot study. Br J Anaesth. 2005;95:596–602
- Elective administration in infants of low-dose recombinant activated factor VII (rFVIIa) in cardiopulmonary bypass surgery for congenital heart disease does not shorten time to chest closure or reduce blood loss and need for transfusions: A randomized, double-blind, parallel group, placebo-controlled study of rFVIIa and standard haemostatic replacement therapy versus standard haemostatic replacement therapy. Blood Coagul Fibrinolysis. 2006;17:389–395
- Recombinant factor VIIa for upper gastrointestinal bleeding in patients with cirrhosis: A randomized, double-blind trial. Gastroenterology. 2004;127:1123–1130
- Control of bleeding in children with dengue hemorrhagic fever using recombinant activated factor VII: A randomized, double-blind, placebo-controlled study. Blood Coagul Fibrinolysis. 2005;16:549–555
- Safety and feasibility of recombinant factor VIIa for acute intracerebral hemorrhage. Stroke. 2005;36:74–79
- Recombinant activated factor VII for acute intracerebral hemorrhage. US phase IIA trial. Neurocrit Care. 2006;4:206–214
- Recombinant activated factor VII in treatment of bleeding complications following hematopoietic stem cell transplantation. J Thromb Haemost. 2005;3:1935–1944
- Recombinant activated factor VII for acute intracerebral hemorrhage. N Engl J Med. 2005;352:777–785
- Recommendations on the use of recombinant activated factor VII as an adjunctive treatment for massive bleeding—A European perspective. Crit Care. 2006;10:R120;(1-12)
- A multicenter assessment of recombinant factor VIIa off-label usage: Clinical experiences and associated outcomes. Transfusion. 2005;45:1434–1442
- . Use of recombinant activated factor VII in the management of intractable haemorrhage: A survey of current UK practice. Br J Haematol. 2007;138:126–128
- Transfusion medicine service policies for recombinant factor VIIa administration. Transfusion. 2004;44:1325–1331
- . Guidelines for the use of recombinant activated factor VII (rFVIIa) in uncontrolled bleeding: A report by the Israeli Multidisciplinary rFVIIa Task Force. J Throm Haemost. 2005;3:640–648
- . Recombinant factor VIIa: A general hemostatic agent? Yes. J Thromb Haemost. 2004;2:1691–1695
- . Off-label reports of new biologics: Exciting new therapy or dubious research? Examples from recombinant activated factor VII. J Intensive Care Med. 2006;21:54–57
- . Medical journals are an extension of the marketing arm of pharmaceutical companies. PloS Med. 2006;2:e138
- . Randomized trials in patients with blunt and penetrating trauma. J Trauma. 2006;60:242–243(letter)
- . Are we giving enough coagulation factors during major trauma resuscitation?. Am Journal Surg. 2005;190:479–484
- . Complications in patients with intracerebral hemorrhage treated with recombinant factor VIIa. Neurology. 2007;69:319–320(letter)
- Thromboembolic adverse events after use of recombinant human coagulation factor VIIa. JAMA. 2006;295:293–298
- Thromboembolic complications associated with factor VIIa administration. J Trauma. 2007;62:564–569
- . Is recombinant FVIIa the magic bullet in the treatment of major bleeding?. Br J Anaesth. 2005;94:553–555
- . Early treatment with recombinant factor VIIa results in greater efficacy with less product. Eur J Haematol Suppl. 1998;61:7–10
- . Recombinant FVIIa for intractable hemorrhage: more questions than answers. Transfusion. 2003;43:1649–1651
- Immediate administration of tranexamic acid and reduced incidence of early rebleeding after aneurysmal subarachnoid hemorrhage: a prospective randomized study. J Neurosurg. 2002;97:771–778
Acknowledgements of research support: National Health Service Blood & Transplant, UK.
PII: S0887-7963(08)00012-6
doi: 10.1016/j.tmrv.2008.02.007
© 2008 Elsevier Inc. All rights reserved.
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Transfusion Medicine Reviews
Volume 22, Issue 3
, Pages 177-187
, July 2008
